i have a 4 year old admitted at present in peads ICU ventilated.Known case of bronchial asthma,also known as brittle asthma .he came in with a very bad attack of asthma with respiratory acidosis and was ventilated.now he is still ventilated and is on iv hydrocortisone ,Iv salbutamol infusion 4 mcg/kg/min , iv terbutaline prn basis (when has desaturation secondary to bronchospasm),nebuliser salbutamol two hourly to hourly , MDI salmeterol 100 mcg bd,MDI inflammide 800 ,cg bd and he still goes for bronchospasm on and off usually secondary to secretion.the secretion are not much.what else can i do for him? he does not seem to be headign to the way of improvement.will MGSO4 helpful to reduce the bronchospam in him.