Other quinolones are not recommended for use in children, though now reports of ofloxacin have been good. For drug of choice, it depends on the local susceptibility pattern. MOst of the enteric cases now are MDR and hence standard drugs such as chloramphenicol, ampicillin and septran do not seem to work. The newer drugs to which the organism is still not resistant is ciprofloxacin, cephalosporins, azithromycin and cefixime. However for ciprofloxacin, the MIC is high and hence a dose of 15mg/kg/dose would be needed rather than 10mg/kg/dose.
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