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Respected sir, I AM FORWARDING HEREWITH my quary and your answer to that. Please refer to the second q i have asked to you which is regardingside effect of NEVIRAPINE. iN OUR PROJECT WE ARE GIVING 6 WEEKS NEVIRAPINE ONLY TO pcr NEGATIVE babies and not as ART TO positive babies.My Q was in our project many babies got neutropenia. As GRANULOCYTOPENIA has been mentioned as very rare side effect and that also in very few articles.So does nevirapine realy leads to neutropenia. Sorry for askng the Q again
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Answer |
Neutropenia is a rare side effect of NVP. A recent study of nevirapine prophylaxis in breast-feeding infants reported several cases of neutropenia in clinically-well infants. These low absolute neutrophil counts may have reflected 'ethnic neutropenia', rather than drug toxicity. This phenomenon has not been confirmed to exist in African infants.
Ref:
Antivir Ther. 2003; 8 (Suppl.1): abstract no. 1039.
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