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| SPECIALIST ANSWERS
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Question |
For prevention of mother to infanttransmission of hiv various trials are used like THAI, ACTG076 &HIVNET.But few physicians and gynacologist use combination therapy like DUOVIR (zidovidine+lamividine OR these two +stavudine or nevirapine DURING ANTENATAL period.(Of course that is justifiable) Iwant to know what retroviral drug to be given to infant of hiv positive mothers when various such combinations are used? 2)A request-"Qustion of the day" is a section where we can read other doctor's answera and opinions and it is definately nice to know othrs views. But it will be also useful if you add expert's answer for that particular qustion. Thanking you Yours sincerely Mangesh
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Answer |
Depending on the protocol being followed, one needs to continue the medication in infants. One cannot prescribe the ART in mothers without a set protocol and the objective that one expects from it. There are also reports of mitochondrial toxicity due to perinatal exposure to ART and hence one needs to monitor the child and mother accordingly. However with all regimes it is recommended that zidovudine be continued in the infant upto 6 weeks and a single dose of nevirapine may also be given if required.
Regarding the question of the day, the answers by pediatriconcall are the experts answers.
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