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Question
If we use different manufacturing company at the time of vaccinatinon means once for hapatitis b we use gsk next time some different company then how much it affects immunity

Answer
If there is no other option, yes, they can be interchanged either during primary doses or when giving boosters. However, it is not ideal or desirable to do so. With many brands coming up it is going to be practically difficult, as a patient may go to a different doctor to complete the course and may get a different vaccine.

For further details, read the article on Hepatitis B vaccine on www.pediatriconcall.com or from the link given below:

http://www.pediatriconcall.com/fordoctor/diseasesandcondition/HepatitisB.asp
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