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Question

please let me the prognosis for a 9 year old child with a diagnosis of GLANDULAR FEVER .I donot have details except that antibodies to CMV are raised . does this mean it is infectious mononucleosis caused by EBV /CMV virus ,Are there long term implicatuions , if so what can the parents look our for. the doctors here do not share information and i would like to help my friend with more than just reassurances and thanks for a good site . It has brought back memories of my student days so many years ago . I would also look for articles on psychosomatic manifestations / chronic stress symptoms and mental health issues of children in your website . thanks again sincerely sandhya

Answer

Are the CMV IgM or IgG raised? If the IgG is raised it may be due to a past infection also. In that case one can do a repeat titre after 4 weeks to look for a four fold rise in titres.
Infectious mononucleosis is a self limiting disease leading to fever, enlarged glands and hepatosplenomegaly. Sometimes rash may be seen. It is commonly seen with CMV and EBV infection.
LOng term implications: EBV may be associated with lymphoma, immunodeficiency and even histiocytosis in genetically susceptible individuals.
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