Spectrum of Renal Tubular Disorders in Iraqi Children
Aamir Jalal Al Mosawi
Department of Pediatrics, University Hospital in Al Kadhimiyia, Iraq
Abstract

Objectives of study: The pattern of renal tubular disorder (RTDs) has been infrequently reported in the literature. In Germany, the three most frequent disorders were cystinosis, X-linked hypophosphatemic rickets (XLHR), and idiopathic hypercalciuria. This study was undertaken to determine the pattern of RTDs in Iraqi and Arab children.

Methods: From June 2000 to April 2007, 42 children with suspected RTD were evaluated to determine the type of tubulopathies.

Results: Ages at referral ranged from 8 months to 14 years (mean 4.8 years). There was evidence of RTD in only 37 patients; 23 males (62 %) and 14 females (38 %). Their ages at referral ranged between 8 months and 14 years (Mean 4.8 years). In 4 patients with oculo-cerebro-renal syndrome, there was no evidence of RTD and one patient has hyperoxaluria which was not a RTD. Seven types of RTDs were identified. The three most common disorders were: idiopathic hypercalciuria (35 %), cystinosis (21.6 %) and renal tubular acidosis RTA (21.6%) Four of the patients with RTA have proximal RTA, and four have distal RTA.Four of the patients with hypercalciuria have also significant hyperoxaluria > 3mg/kg/day.

Conclusion: Common RTDs in Iraqi children are idiopathic hypercalciuria, cystinosis and RTA and differs from those reported elsewhere.
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