Objective: To study the effect of multimicronutrient supplementation to malnourished pregnant women on the birth weight and early neonatal outcome.
Design: Randomized control trial
Settings: Department of Pediatrics & Gynecology and Obstetrics, LLRM Medical College, Meerut.
Methods and Materials: 350 pregnant women carrying singleton pregnancy, any gravidity with body mass index (BMI) < 21, and hemoglobin between 7 - 9 gm/dl without established risk factors were enrolled in the study at 20 weeks of pregnancy. They were divided into 3 groups. First group was given multi micronutrient supplement from 20 weeks to term, second group from 20 weeks to 30 weeks, and the third was given placebo tablets. At the time of delivery, birth weights, neonatal anthropometry, were recorded and the babies were followed up for 7 days for complication. All the recorded data was analyzed using Chi-square test.
Results: An increase of birth weight by 185 gm was found in that group who were supplemented for longest period than the placebo group and difference in the birth weight among any 1st and any of the other 2 groups were statistically significant (p=.001 in 1st and 3rd, 0.1 in 2nd and 3rd, 0.02 in 1st and 2nd group). The number of sick neonates was significantly increased in placebo group (40.58%) as compared to the two supplemented groups (20.58% and 23.81 % respectively).
Conclusion: Based on the result of above study it can be said that multi-micronutrient supplementation to malnourished women reduces the risk of Low birth weight (LBW) and early neonatal morbidity.