This observational study was done to find out the incidence and pattern of childhood poisoning, to know the morbidity and mortality resulting from childhood poisoning and to analyze the outcome. One hundred sixty five children aged between 0-18 years were admitted to the pediatric ward with history of poisoning during the six year period of the study (August 1999-July 2005). The incidence of childhood poisoning was 1.28%. In this study commonest age group affected was between 11-18 years (76.5%). Male to female ratio was 1.17:1. Majority of cases, 158 (95.7%) were seen from low and middle socioeconomic group and 134 (81.2%) belonged to rural area. The commonest mode of presentation was vomiting in 100 (60.6%) patients and 99 (60%) patients were brought to hospital after 5 hours of exposure. In the present study, 63 (38.2%) of cases were due to poisoning by insecticides and pesticides, followed by plant poisoning in 36 (21.8%) whereas kerosene oil poisoning was seen in only 8 (4.9%) patients. Accidental poisoning was seen in 153 (92.7%) patients. Ten (6.1%) patients died and 96 (58.1%) of patients stayed in hospital for only 1-2 days.