TUMORAL CALCINOSIS
Baghaie Nooshin, Mohamadi Forouzan, Khodayari Amir Ali
Department of Pediatrics, National Research Institute of Tuberculosis and Lung Disease, Iran
Address for Correspondence
Baghaie Nooshin, National Research Institute of Tuberculosis and Lung Disease; P.O.BOX: 19575-154, Tehran, Iran.
Email
dramiralikh@yahoo.com
Tumoral calcinosis is a rare disorder with the calcified masses in subcutaneous tissues. We report herein a fourteen-year-old boy, in whom the calcified lesions involved the soft tissues in the anterior part of the knee joint, iliac fossa and anterior of leg with abscess formation and periodically, a chalky semifluid material extruded through several cutaneous sinuses.

In laboratory findings ESR was normal, gastric washing was negative, serum level of calcium, phosphor and PTH were normal, alkaline phosphates was 618 IU/L and PPD was negative, Chest X-ray and CT-Scan of thorax were normal. Radiography of right leg demonstrate platy and linear deposition of calcium in distal of tibia (fig 1)and a typical appearance of amorphous, cystic, and multilobulated calcification in iliac fosse .( 2Fig)

Figure 1- Radiography of right leg demonstrate platy and linear deposition of calcium in distal of tibia

Figure 2- Typical appearance of amorphous, cystic, and multilobulated calcification in iliac fossa


Histological examination of removal tumor was compatible with Tumoral calcinosis.

In the mid-1960s, reviews established that tumoral calcinosis had a familial tendency without sex predominance but with a significantly higher incidence in patients of African descent.(1,2,3) Our case had not any family history of tumoral calcinosis or metabolic disorder due to calcium and phosphate homoeostasis.

According to that tumoral calcinosis is a rare condition and a little number of such cases were reported in our area, here in we report this patient with unusual presentation that can mimic tuberculosis of skin.

On the contrary, tumoral calcinosis is a rare familial disease that in such cases evaluation of patient's siblings should be mentioned.
Funding
None
Conflict of Interest
None
References :
  1. Harkess JW, Peters HJ. Tumoral calcinosis: a report of six cases. J Bone Joint Surg Am 1967; 49:721-731.
  2. Harkess JW, Peters HJ. Tumoral calcinosis: a report of six cases. J Bone Joint Surg Am 1967; 49:721-731.
  3. Lafferty FW, Reynolds ES, Pearson OH. Tumoral calcinosis: a metabolic disease of obscure etiology. Am J Med 1965; 38:105-118.
Last Updated : Sunday, February 01, 2009 Vol 6 Issue 2 Art #7
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Nooshin B, Forouzan M, Ali A K. TUMORAL CALCINOSIS. Pediatric Oncall [serial online] 2009[cited 2009 January 1];6. Art #7. Available From : http://www.pediatriconcall.com/Journal/Article/FullText.aspx?artid=58&type=J&tid=&imgid=&reportid=293&tbltype=
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