Aplasia Cutis Congenita
Jagdish Kathwate
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Aplasia Cutis Congenita - Patient Education
What is aplasia cutis?
Aplasia cutis is a condition where a newborn child is missing skin from certain areas. In about 70% of cases it is a single lesion on the scalp, but sometimes multiple lesions may appear on other parts of the body. They vary in size from 0.5cm to 10cm.Lesions that involve only the epidermis (upper layers of skin) are shallow and usually heal over with scarring before the child is born. A deeper lesion involving the dermis, subcutaneous tissue, or rarely, the skull may be ulcerated.Membranous aplasia cutis is the term used when there is an underlying flat, white membrane, which overlies a defect in the skull. It can be associated with a neural cranial tube defect (encephalocoele or meningocoele), which can be demonstrated by ultrasound scan showing misplaced brain tissue outside the skull.

Who is at risk?
It is not yet fully known why aplasia cutis occurs but the following factors may be involved:
Genetics: aplasia cutis may be seen in association with other congenital skin defects such as epidermal naevi
Teratogens (drugs or chemicals causing birth deformities)
Defect in skin development in the embryo/fetus
Early rupture of amniotic membranes
Aplasia cutis affecting the limbs may be associated with the death of a twin fetus (papyreous fetus)

What treatments are available for It?
Small areas of aplasia cutis usually heal spontaneously over time. To prevent infection gentle cleaning and bland ointments may be used. If infection occurs antibiotics can be used. Larger lesions may require surgical repair.

What are the complications for aplasia cutis?
Complications rarely occur but may include:
Arterial bleeding
Secondary infection


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