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DRUG RELATED (IATROGENIC) ABNORMALITIES & SERUM ARTEFACTS
PATTERN IN SALICYLATES INGESTION

Commonest cause of high uric acid level is salicylates ingestion . Diuretics also raise uric acid levels.

BIOCHEMICAL TEST NORMAL RANGE PATIENT VALUES
LOW NORMAL HIGH
S. URIC ACID 2.1 – 7.4 mg / dl     10

PATTERN FOLLOWING DIURETIC THERAPY

Elevated uric acid and low Na+ and Cl levels are commonly observed

BIOCHEMICAL TEST NORMAL RANGE PATIENT VALUES
LOW NORMAL HIGH
CALCIUM A à 8.5 – 10.5 mg / dl
C à 9.5 – 11.0 mg /dl
  9.2  
PHOSPHORUS A à 2.5 – 4.5 mg / dl
C à 2.5 – 5.5 mg / dl
  3.8  
S.URIC ACID 2.1 – 7.4 mg / dl     10
SODIUM 137 – 148m.Eq / L 127    
POTASSIUM 3.5 – 5.6m.Eq / L   4.5  
CHLORIDES 99 – 108m.Eq / L 92    
BICARBONATE 23.7 – 31.4m.Eq / L   27  
  A à Adult. C à Child,      

PATTERN OF HEMOLYSED SERUM

Depending upon degree of hemolysis (in vitro), L.D.H., H.B.D.H. & S.G.O.T. will be elevated.

BIOCHEMICAL TEST NORMAL RANGE PATIENT VALUES
LOW NORMAL HIGH
H.B.D.H.(UV KINETIC) 90 –220 IU / L     275
L.D.H(UV KINETIC) 40 – 110 IU /     195
S.G.O.T.(UV KINETIC) 7 – 24 IU / L     30

PATTERN OF NON – FASTING SAMPLE

High levels of triglycerides, cholesterol, urea & alkaline phosphatase may be observed in non fasting samples.

BIOCHEMICAL TEST NORMAL RANGE PATIENT VALUES
LOW NORMAL HIGH
TRIGLYCERIDES 35 – 165 mg / dl     385
CHOLESTEROL(Enzymatic) 125 – 225 mg / dl   210  
ALK. PHOSPHATASE(KINETIC) A à 15 – 65 IU / L
C à 70 – 150 IU / L
    70
BLOOD UREA(KINETIC) 15 – 45 mg / dl   43  
  A à Adult. C à Child,      


Last updated on 6-11-2000
 
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