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Recurrent Abdominal Pain In Children
COMPED 2006

Dr. Subhash Agrawal

Senior Consultant, Pediatrician & Neonatologist
Moolchand Hospital & Tirathram Hospital , Delhi
Recurrent Abdominal Pain (RAP)

  • Common Pediatric Problem, Age : 4-16 yrs.
  • Apple’s Definition : Paroxysmal Abdominal pain, Persists> 3 mths., Affects normal activity.
  • Chronic pain abdomen : If persists> 6 mths.
  • Incidence : Equal till 9 yrs., Then> in Males
  • Adolescents : 75% Suffer, 21% severe pain
  • Approx. 10% Abdominal pain – Seek medical help
  • Mostly in RAP : No identifiable cause
  • Exclude organic cause : Before labeling functional etiology.
Common Clinical Presentations

  • Isolated paroxysms of abdominal pain
  • Abdominal pain ass. With dyspepsia
  • Abdominal pain ass. With altered bowel habits
Common Organic Causes

  • G.I. Tract : Chronic constipation, Esophagitis, Lactose intolerance, Parasitic infestation., Excess Fructose/Sorbitol Ingestion, Crohn’s disease, Peptic Ulcer, Appendicitis, Cholelithiasis, Choledochal Cyst. & Pancreatitis etc.
  • G.U.Tract: UTI, Hydronephrosis, Urolithiasis etc.
  • Miscellaneous : Abdominal Epilepsy, Lead Poisoning Porphyria, Henoch-Schonlein
    Purpura, Angioneurotic Edema, Gilbert Syndrome, Sickle Cell Crisis etc.
Clues to an Organic Cause

  • Age : <6 yrs, Pain away from Umbilicus.
  • Severe pain – Sudden onset, Sleep disturbed
  • Fever, Vomiting, Diarrhea, Blood in stool
  • Age : <6 yrs, Pain away from Umbilicus.
  • Abdominal distention, Dysuria, jaundice
  • Reduced activity, Short stature – Abnormal growth.
  • No emotional stress or positive family history

Functional RAP
Also known as
  • Psychogenic abdominal pain
  • Functional abdominal pain
  • Periodic syndrome
Functional RAP

  • Indicator of psychological disturbances
  • High frequency of behavioral disorders
  • Evidence of maladjustment, Anxiety reactions
  • High strung perfectionists and apprehensive personalities, have no evidence of disease
  • Past H/o Colic & feeding problems in infancy
  • Family H/o Abdominal pain present
  • Stress within the family and/or at school <
Functional RAP
Associated with 5 major paediatric disorders
  • Inflammatory bowel syndrome
  • Functional dyspepsia
  • Abdominal migraine
  • Aerophagia
  • Functional abdominal pain syndrome
Rome II Guidelines – Functional RAP
Features of Inflammatory bowel syndrome :
  • Abnormal stool frequency (>3/d or <3/week
  • Abnormal stool form : Lumpy, hard or loose
  • Abnormal stool passage : Straining, Urgency, feeling of incomplete defecation.
  • Passage of mucus, Bloating, Feeling of abdominal distention.
Rome II Guidelines for IBS

  • Child old enough to provide accurate H/O pain
  • Pain present for at least 12 wks in previous 12 months – Not necessarily consecutive
  • Pain is relieved with defecation or change in stool form or frequency
  • No structural/metabolic abnormalities present to explain the symptoms
Rome II Guidelines – Functional dyspepsia

  • Pain centered in the upper abdomen (Above Umbilicus) for 12 wks in previous 12 months
  • No evidence of organic disease
  • Dyspepsia neither relieved by defecation nor by change in stool frequency or form
Rome II Guidelines – Abdominal migraine

  • 3 or more paroxysmal episodes
  • Intense, Acute, Midline abdominal pain
  • Lasting for 2 hrs to several days
  • Intervening symptom free interval : wks to months
  • No evidence of metabolic, GI or CNS disease
  • Any 2 of the following features presents:
  • Headache, confined to one side only
  • Photophobia – family history of migraine
  • An aura of visual, sensory or motor symptoms
Rome II Guidelines – Aerophagia
Presence of 2 or more of the following:
  • Air swallowing Abdominal distention :
  • Due to intra-luminal air
  • Repetitive belching or increased flatus
Rome II Guidelines
Functional abdominal pain syndrome
  • Continuous pain in elderly child or adolescent
  • No relation with eating, defecation, menses
  • Some loss of daily functioning
  • Pain is not feigned
  • No other associated organic GI disorder
Clues to a Functional Causes

  • Age of onset :> 6 years
  • Para-umbilical, midline paroxysmal pain
  • No consistent duration, frequency periodicity of pain
  • Brief pain with intervals from days to weeks
  • Child unable to pin-point the exact site of pain
  • No radiation, no relation with meals
  • Sleep or pleasure activities – not interfered
  • Normal growth, no weight loss, O/E – Normal
  • Emotional stress present or positive family history
  • RAP children have autonomic nervous system and abnormal intestinal motility
Investigations

  • Complete blood counts. Hb, ESR (Raised in IBS)
  • Urinalysis and culture, stool-parasites and occult blood.
  • Upper GI X-rays, Abdominal ultrasound
  • If Peptic Ulcer : H. Pylori antibody test or endoscopy
  • If pancreatitis : Serum amylase during active pain
  • LFT in suspected hepato – Biliary disorders
  • Others : EEG, GI Barium studies, IVP, CT Scan, Cholecystography, Endoscopy & proctoscopy.
Treatment – Dietary
  • In IBS : No food rich in fat, alcohol and caffeine
  • Avoid high sorbitol high fructose foods as they cause increased gas production and intestinal distention.
Cochrane review:

  • Lack of evidence on effectiveness of diet
  • Fiber supplements are not effective
  • Lactose restricting diets are inconclusive
  • Need for well designed trials for dietary interventions in functional RAP.
Treatment – Pharmacological
Cochrane Review
  • Recommended drugs : Not very effective
  • Lactose intolerance : Lactose fee diet
  • Gastro-esophageal reflux : Acid blockers
  • IBS & loose stools : Fiber supplementation
  • Anticholinergics and Antidepressants : In some patients
  • Abdominal migraine : Anti-migraine drugs e.g., Pizotifen Prophylaxis – useful.
  • Chronic constipation : Standard treatment
  • Close follow up of the patients : Must
Treatment – Psychological
Cochrane Review
  • Good evidence : Relaxation and cognitive behavioral therapy are effective in reducing the severity and frequency of pain.
Prognosis

  • Many children with RAP : Continue to suffer in adult life from symptoms of IBS
  • Poor Prognosis:
  1. Early development of symptoms
  2. Delayed treatment
 
Last Updated on 15-01-2007

How to cite this url
Comped 2006 - Conference Abstracts.Pediatric Oncall [serial online] 2007 [cited 15 January 2007(Supplement 1)];4. Available from:
http://www.pediatriconcall.com/fordoctor/Conference_abstracts/
comped/Abdo.asp
 
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