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CLINICAL AND IMMUNOLOGICAL PROFILE OF HIV IN CHILDREN
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OOTY PEDICON – 2005
Dr Arunkumar J, Dr Rajamurali S, Dr Lakshmi S, Dr Kumarasamy K, Dr Sundaraman PG, Dr Vasanthamallika TK
ICH & HC
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Objective:
To study and correlate the clinical and immunological profile of HIV in children.
Design:
Prospective. Setting: HIV clinic at a pediatric tertiary care center in an urban metropolis.
Subjects & Methods:
48 HIV positive children between 1½ and 12 years were included with a minimum follow up period of one year.
Results:
Majority of children (45.8%m n = 22) were under 3 years of age. Recurrent febrile illness and recurrent respiratory infection were the commonest presenting illness 91.7% and 81.3% respectively. Tuberculosis was found in 54.2% (n = 26) and malnutrition was found in 97.9% (n = 47). According to the CDC clinical categorization, majority were in category B (47.9%, n = 23). Baseline mean CD4+ T cell count and total leucocyte count were 459.7 (9 – 3060) and 4046.34 (100 – 15,300) respectively. 52.1% by CD4+ T cell count and 68.8% by CD4+ T cell percentage were in immunological category III
Conclusion:
The clinical presentation in children is different from that in adults with rapid progression and late diagnosis in children. There is also a significant increase in immune response with simple supportive measures.
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Last Updated on 01-12-2005
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Ooty Pedicon 2005 - Conference Abstracts.Pediatric Oncall [serial online] 2005 [cited 01 December 2005];2. Available from:
http://www.pediatriconcall.com/fordoctor/Conference_abstracts/ hiv_clinical.asp
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