XVII Annual Conference of IAP Maharashtra State (Mahapedicon 2006, Solapur, 3-5th November 2006)

Dr. U. R. Warerkar, M.D., DCH, Head of Dept., Dr. Vijaykumar Gutte, Registrar
Department of Paediatrics, Ashwini Sahakari Rugnalaya & Research Centre, Solapur

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Case History: 5 years old male child, having blisters arranged in annual form mostly around crusted healing lesion involving lower trunk, buttocks, genitals, thigh patient had right sided corneal opacity suggestive of mucosal involvement. On skin biopsy infiltration of neutrophils at dermoepidermal junction. Patient had normocytic normochronic anemia. Patient was treated with Dapsone 2 mg/kg/day, Prednisolone 2 mg/kg/day, Chronic bullous dermatosis of childhood is childhood form of liner IgA bullous dermatosis. (LAD)

It is rare autoimmune subepidermal blistering disease with neutrophilic infiltrate circulating IgA antibasement membrane zone antibody and liner deposition of IgA along Dermoepidermal junction. It begins by the age of 2 to 3 years and remits by the age of 13 years. Site of involvement is lower trunk, buttocks, genitals, thigh, periocular and perioral area. Onset is abrupt with large tense bullae developing near genitals. The bullae are filled with clear or hemorrhagic fluid. Bullae are arranged in rosette or annular array so caused clusters of jowell configuration. There is annular arrangement of new/small tense blisters around crusted healing erythematous plaque. Mucosal involvement leads to conjunctival scarring.


Last Updated on 01-04-2007