CHRONIC BULLOUS DERMATOSIS OF CHILDHOOD (Childhood form of LAD)
Dr. U. R. Warerkar, M.D., DCH, Head of Dept.*, Dr. Vijaykumar Gutte, Registrar**
Department of Paediatrics, Ashwini Sahakari Rugnalaya & Research Centre, Solapur.*, Department of Paediatrics, Ashwini Sahakari Rugnalaya & Research Centre, Solapur.**
Case History: 5 years old male child, having blisters arranged in annual form mostly around crusted healing lesion involving lower trunk, buttocks, genitals, thigh patient had right-sided corneal opacity suggestive of mucosal involvement. On skin biopsy, infiltration of neutrophils at dermoepidermal junction was seen. Patient had normocytic normochromic anemia. Patient was treated with Dapsone 2 mg/kg/day, Prednisolone 2 mg/kg/day, Chronic bullous dermatosis of childhood is childhood form of Liner IgA bullous Dermatosis. (LAD)

It is a rare autoimmune subepidermal blistering disease with neutrophilic infiltrate circulating IgA antibasement membrane zone antibody and liner deposition of IgA along dermoepidermal junction. It begins by the age of 2 to 3 years and remits by the age of 13 years. Site of involvement is lower trunk, buttocks, genitals, thigh, periocular and perioral area. Onset is abrupt with large tense bullae developing near genitals. The bullae are filled with hemorrhagic fluid or clear. Bullae are arranged in rosette or annular array so caused clusters of jewel configuration. There is annular arrangement of new/small tense blisters around crusted healing erythematous plaque. Mucosal involvement leads to conjunctival scarring.
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