NATWAR SHARMA*, EZHILARASI. S**, SARALA RAJAJEE***
Kanchi Kamakoti Childs Trust Hospital. *, Kanchi Kamakoti Childs Trust Hospital. **, Kanchi Kamakoti Childs Trust Hospital. ***
Autoimmune Hemolytic Anemia is an entity resulting due to autoantibodies directed against red blood cells.
|To study the children with autoimmune hemolytic anemia, with respect to |
etiology, triggering factors and complications.
Prospective descriptive study. Setting: Department of Hematology, from 1996-2005. Kanchi Kamakoti CHILDS Trust Hospital. Subjects and methods: 10 children with autoimmune hemolytic anemia in the age group 7 months to 15 years with equal male: female ratio and followed up over a period between 8 months to 10 years to assess the etiology, triggering factors for relapse, longterm outcome and complications.
|We had 10 children with Autoimmune Hemolytic Anemia in the age group of 7 month to 15 years. There were equal number of male and female children. Pallor (100%), fever (90%), Hepatosplenomegaly (70%), jaundice (50%) were the |
most common presenting features. 8 (80%) were idiopathic. Among them 6 (60%) were positive for warm antibodies and 2 (20%) were positive for cold antibodies, 2 (20%) were Anti Nuclear Antibody positive Systemic Lupus Erythematosus. All children received methylprednisolone followed by oral steroids. On follow-up 3 (30%) were well, 7 (70%) children relapsed all of which were precipitated by minor infections, 4 (40%) had only one relapse. One child was lost for follow-up. There was no mortality.
|Autoimmune Hemolytic Anemia is a potentially fatal disease, which requires rapid recognition and continuing therapy. |
Relapse occurred in 7 (70%) of children associated with minor infections. 2 (20%) were part of Systemic Lupus Erythematosus. Mortality was nil.
|Autoimmune Hemolytic Anemia, Therapy, Outcome. |
|How to Cite URL :|
|SHARMA N, S E, RAJAJEE S.. Available From : http://www.pediatriconcall.com/fordoctor/ Conference_abstracts/report.aspx?reportid=30|