Rajeswari N*, Suchitra R**, Deepika ***
Dept of PICU, Apollo Hospitals, Chennai. *, Dept of PICU, Apollo Hospitals, Chennai. **, Dept of PICU, Apollo Hospitals, Chennai. ***
|A pilot study to assess efficacy and safety of titrated doses of sedatives and analgesics in |
|Five cases were included in the study from Jan 2005 onwards. Brief history, physical examination including |
oropharyngeal examination and categorization under ASA classification were carried out and all cases were kept NBM for three hours prior to the procedure. Midazolam / ketamine / glycopyrrolate, midazolam / propofol combinations were given for various noninvasive (painless) and invasive procedures.
Airway integrity, pulse and respiratory rates, oxygen saturation and Ramsay sedation scoring were documented every 5 minutes until recovery.
|Of the 35 cases enrolled in our study, 14 cases received ketamine and midazolam combination as titrated boluses at half the recommended doses and 13 cases received midazolam / propofol. Three patients received propofol along as bolus followed by infusion for MRI. The remaining 5 cases received midazolam along for short imaging studies. All complications were observed in the 3 patients that received only propofol. None of the patients on midazolam / ketamine / glycopyrrolate had untoward complications. |
|The interim results of this |
small pilot study appears to indicate that -
- Titrated boluses of small dose of midazolam / ketamine combinations appear to minimize side effects with good analgesia and amnesia and early recovery.
- Propofol bolus followed by infusions may be associated with
|How to Cite URL :|
|N R, R S, Deepika.. Available From : http://www.pediatriconcall.com/fordoctor/ Conference_abstracts/report.aspx?reportid=316|