DO WE HAVE TO SCREEN FOR G-6 PD DEFICIENCY IN NEONATAL JAUNDICE?
Dr. VIDHYA KRISHNAN*, Dr. LUKE RAVI CHELLIAH**, Dr. D. GUNASINGH***, Prof. MEER MUSTAFA HUSSAIN****, Prof. SARADHA SURESH*****, Prof. MANGAYARKARASI SENGUTTUVAN ******
Institute of Child Health and Hospital for Children.*, Institute of Child Health and Hospital for Children.**, Institute of Child Health and Hospital for Children. ***, Institute of Child Health and Hospital for Children. ****, Institute of Child Health and Hospital for Children. *****, Institute of Child Health and Hospital for Children.******
Aim
To estimate the prevalence of G-6-PD deficiency among jaundiced neonates.
Methods
The study was conducted in a prospective manner at the out-born newborn unit of ICH & HC, Egmore, Chennai. It was cross sectional study among neonates with significant hyperbilirubinemia. The sample size was 50. The UV kinetic methods (spectrophotometric assay) was used for quantitative estimation of G-6 PD levels in neonatal RBC's. In addition, data on age, sex, maturity, consanguineous marriage, birth weight, hemoglobin levels, serum bilirubin, co-morbid illnesses etc. were also recorded.
Conclusion
The prevalence of G-6-PD deficiency among jaundiced neonates was found to be low (2%). Routine screening for G-6 PD deficiency among jaundiced neonates is not recommended.
Keywords
G-6 PD, hyperbilirubinemia, jaundice, neonate, prevalence
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KRISHNAN V D, CHELLIAH R L D, GUNASINGH D D, HUSSAIN M M P, SURESH S P, SENGUTTUVAN M P.. Available From : http://www.pediatriconcall.com/fordoctor/ Conference_abstracts/report.aspx?reportid=38
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