Effectiveness of Total Parenteral Nutrition in Infants’ Growth
Effectiveness of Total Parenteral Nutrition in Infants’ Growth
Chee Yuan Tang*
University of Aberdeen, UK*
Abstract
Introduction: Preterm infants are known as group of population with high mortality and morbidity due to anatomical or functional prematurity. However, the risk of developing complications reduces with increasing gestational age and birth weight. Hence, it is crucial to provide rapid aggressive nutritional support to maintain an optimal postnatal growth.

Aims: To assess the efficacy of aggressive total parenteral nutrition (TPN) support in low birth weight infants.

Methods: This study is conducted at Neonatal Intensive Care Unit (NICU), Penang General Hospital. All infants receiving TPN at NICU from year 2012 to year 2013 were included in this study. Infants who were discharged or died within 7 days of admission or received parenteral nutrition only were excluded from the study.

Results: 45 admissions were accepted in the study. All infants were born between 25 to 36 gestational weeks where the ages of the mothers range from 21 to 43 years old. The mean daily weight gain for SGA and AGA infants were recorded as 17.02g and 6.10 respectively. The growth of head is unsatisfactory, <0.7cm/week.

Conclusions: TPN support is more beneficial for infants who born SGA compared to infants who born AGA. However, the risk of developing complications did not alter. There is still lack of evidence to support the overall benefits of early administration of protein and lipid in newborn. Further studies are needed to determine the outcomes in this population.
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