Diagnosis of Systemic Lupus Erythematosus (SLE) | Pediatric Oncall
Last Updated : 12/10/2006
Dr Gurmeet Mangat
The diagnosis is made in the presence of at least 2 appropriate clinical features and strongly positive antinuclear antibody test (ANA) and a positive dsDNA test. The point to note is that ANA should be done by immunofluorescence method and a titre of more than 1:80 is significant.

Differential diagnosis:
Infections are common in our setting and specific infections like tuberculosis should be ruled out. In children, malignancies of the blood and lymph nodes have to be carefully eliminated.

Contributor Information and Disclosures

Dr Gurmeet Mangat
Consultant Rheumatologists, P.D.Hinduja Hospital, Mumbai, India

First Created : 12/10/2001
Last Updated : 12/10/2006


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