Asthma Common Drugs - Leukotriene Antagonists and inhibitors

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ASTHMA IN CHILDREN

Dr C.T.Deshmukh
Professor of Pediatrics, K.E.M Hospital

Common drugs used in Asthma

Continued...

Leukotriene antagonists and inhibitors.

First new class of anti Asthma drugs in more than 25 years.

They can either block leukotriene receptors (Zafirlukast, Montelukast) or inhibit enzyme 5 lipoxygenase ( Zileuton).

They produce long-term bronchodilatation.

Main advantage is that they can be taken orally once or twice a day.

They may be used instead of steroids in children more than 5 years of age who have mild persistent asthma. They can also be used along with steroids to reduce the doses of steroids. Exact role in management is still evolving.

Long acting Inhaled β 2 agonist

They are used as adjunct to inhaled steroids and other anti-inflammatory agents. Never to be used as single drug therapy.

Can be used in nocturnal symptoms.

Not to be used for acute attacks.

Available as dRotacaps d Inhaler or diskhaler.

Given as 25 µg per dose twice a day.

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ASTHMA IN CHILDREN : EXPERTISE VIEWS

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Use of Spirometer in Pediatric Patients other than using for diagnosis?

About bronchial asthma related to MGSO4(Mag sulphate)?

About no cold freon effect of spacers used in asthma?

Role of FeNo2 in management of Asthma?

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