Zinc for Prevention of Diarrhea

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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ZINC FOR THE PREVENTION OF DIARRHEA

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Introduction

Prevention of Diarrhoea

Evidence for Zinc in Prevention of Diarrhea

Santosh Singh
Medical Sciences Department,Pediatric Oncall

Address for Correpondence:

Dr Santosh Singh,Medical Sciences Department, Pediatric Oncall, 1/B Saguna, 271/B St. Francis Road, Vile Parle (W), Mumbai 400056.

Diet and Zinc

Despite the widespread presence of zinc in common foods, dietary deficiency is common because biovailability of zinc is reduced by the coexistence of inhibitory substances such as fiber and phytates in food of vegetable origin. These substances inhibit the absorption of zinc. The diets of the poorest populations are a poor source of zinc being largely made up of vegetable staples with little content of animal products, especially flesh foods such as meat, fish which are rich sources of easily assimilated zinc. Children in these communities do not manifest obvious signs of zinc deficiency but have often been found to have low plasma zinc levels compatible with subclinical zinc deficiency. Unlike other essential micronutrients like iron and vitamin A, there are no conventional tissue reserves of zinc that can be released or sequestered quickly in response to variations in dietary supply.(3)

Given the diverse array of biological functions of zinc, it is not surprising that multiple physiological and metabolic functions, such as physical growth, immunocompetence, reproductive function, and neurobehavioral development are all affected by zinc status. When the supply of dietary zinc is insufficient to support these functions, biochemical abnormalities and clinical signs may develop. Recent investigations suggest that Zinc deficiency may be contributing to the high illness rates in these populations.(3)

Thus, zinc supplementation of high risk populations has considerable potential and the search for simple economic options to counteract zinc deficiency should be given priority.

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