4th Pediatric Infectious Diseases Conference
 
 
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Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
INFLAMMATORY BOWEL DISEASE (IBD)
INFLAMMATORY BOWEL DISEASE (IBD)
Prof. (Dr) Sharad C Shah
Consultant Gastroenterologist
Ex Head Department of Gastroenterology
Sir J J Hospital & Grant Medical College
Hon Gastroenterologist - Sir H N Hospital
Hon Gastroenterologist - Jaslok Hospital
Hon Gastroenterologist - Breach Candy Hospital

Q. What are the various other symptoms that may be seen in patients with IBD?
A. The other symptoms of IBD are:

Ulcerative colitis: The extra-intestinal manifestations are the same as Crohn's disease but in some ways they vary. The eyes, mouth, skin, joints are involved more frequently in UC. Liver disease (Primary sclerosing cholangitis) is seen in 3% of all patients.

The other rare associations are pericarditis with or without effusion and amyloidosis.

Crohn's disease : Patient may have obstruction, fistula formation (they can develop entero-enteral fistula, enterovesical fistula enterovaginal fistula and enterocutaneous fistula) and intra-abdominal abscess. The extra-intestinal manifestation will be
  • Colitis related
  • Consequence of small bowel pathophysiology
  • Miscellaneous
  • Colitis Related: Peripheral arthropathy, erythema nodosum, episcleritis, fatty liver, aphthous ulcers (10%), pyoderma gangrenosum (1-2%). Clubbing, pelvis osteomyelitis and osteomalacia.
  • Consequences of small bowel pathophysiology : Malabsorption, gall stone formation (15-30%). Steatorrhea, diarrhea, bacterial overgrowth may lead to surgical resection. Pancreatitis.
  • Miscellaneous : Amyloidosis, thrombo-embolic phenomenon, hepato biliary disease - primary sclerosing cholangitis.
1/4th of patients present with CD before 20 years of age. Arthritis and arthralgia are seen in about 15% of children. There may also be growth failure, anemia and delayed puberty.


Q. How does one diagnose IBD?
A. Diagnosis of IBD :

Crohn's disease:
  • Usually presents as abdominal pain, may have frequent stools and blood in stools.
  • Routine hemogram, stool - routine and microscopy.
  • On Clinical suspicion - Endoscopy - appearance & biopsy
  • Barium contrast studies - barium enema
  • Ultrasonography
  • CT Scan may help
Ulcerative colitis :
  • Usually presents as bloody diarrhea.
  • Routine hemogram, stool - routine and microscopy.
  • C - reactive protein (CRP), albumin - for follow-up and prognostication.
  • Sigmoidoscopy / Colonoscopy - appearance & biopsy
  • Radiology - Barium Enem

 
 
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