4th Pediatric Infectious Diseases Conference
 
 
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FIND DIAGNOSIS
FIND DIAGNOSIS
Find Diagnosis
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
APPROACH TO A CASE OF ATAXIA
Approach to Case of Ataxia
Acute Ataxia and Cerebellar Ataxia Investigations
Acute Ataxia and Cerebellar Ataxia Investigations
Dr Ira Shah
M.D, DCH(Gold Medalist), FCPS, DNB
Edited by
Dr Sarosh M Katrak MD, DM, FIAN
Consultant Neurologist


Continued...

ACUTE ATAXIA Acute Ataxia Causes

Acute ataxia with rapid improvement:

The two commonest causes are:

  1. Drug Ingestion
  2. Acute post infectious cerebellitis

    Drug Ingestion: Accidental drug ingestion is highest between 1 and 4 years of age. Overdose of hypnotics, tranquilizers, toxic doses of anticonvulsants especially phenytoin and carbamazepine may cause ataxia and nystagmus. If a child is on too high a dose of phenytoin, it usually takes 5-10 days for the ataxia to develop and about the same time after stopping or reducing the dose for the symptoms to disappear. Acute intoxication with glue, solvents, petrol, alcohol, antihistamines may also cause ataxia. It is diagnosed on the basis of history and urine examination for drug metabolites and blood for toxic analysis.

    Acute cerebellar ataxia (Post infectious acute cerebellitis): It is usually seen in children between 2 to 7 years with a very sudden onset. It is often preceded by an exanthema (varicella), infectious mononucleosis or other viral infections (polio, mumps, coxsackie, herpes, simplex or ECHO viruses). It is thought to occur due to an autoimmune response to the viral agent. Ataxia is maximum at the onset. Symptoms are non-progressive for a couple of days or weeks and then subside. (Recovery may take 3 weeks to 5 months). Recovery is usually complete. It is a diagnosis of exclusion. Tendon reflexes are usually present (absence may suggest Miller Fisher syndrome). It's a self-limiting condition and treatment is usually not required.
Acute ataxia with prolonged or intermittent course

The commonest conditions to keep in mind are:

  1. Myoclonic Encephalopathy (Dancing eye syndrome)
  2. Neuroblastoma syndrome
  3. Brain Tumors
  4. Multiple sclerosis
  5. Metabolic disorders


 
 
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