4th Pediatric Infectious Diseases Conference
 
 
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Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
NON - HODGKIN'S LYMPHOMA (NHL)
Non Hodgkin's Lymphoma (NHL)
Dr Ira Shah
M.D, DCH(Gold Medalist), FCPS, DNB
Edited by Dr. Bharat R Agarwal
Consultant Pediatric Hematologist and Oncologist.


Q: What are the complications of NHL?

A: There are 2 potentially life threatening complications seen in children with NHL.
  • Superior vena cava syndrome is seen usually in lymphoblastic lymphoma.

  • Tumor lysis syndrome is seen usually in small non-cleaved cell NHL.

( for more information, see Oncologic Emergencies ).

Q: How do you manage a relapse?

A: The chances of relapse are greatest in the 1st 6 - 12 months from diagnosis. Relapse indicates a poor prognosis.

Treatment of relapse is as follows :-

Recurrent lymphoblastic lymphoma :-
  • Allogenic bone marrow transplant.

  • Previously unused chemotherapy regime.

  • Radiation
Recurrent small non - cleaved cell lymphoma :-
  • High dose cytarabine with other agents particularly etoposide and ifosfamide.

  • Allogenic or autologous bone marrow transplant.

  • Treatment using regimes used in stage III or IV
Recurrent Large cell lymphoma :-
  • Allogenic or autologous bone marrow transplantation.

  • Treatment using regimes used under stage III or IV of small non-cleaved cell lymphoma.

See the biochemical profile in disseminated lymphoma

Last created on 13-07-2001
Last updated on 01-07-2006

 
 
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