|NEWER TYPE OF INTERFERON FOR HEPATITIS C|
Until recently, interferon was the only treatment for hepatitis C - an infection leading to cirrhosis with a mortality of about 10,000 people every year. Interferon is effective in reducing Hepatitis C viral load substantially within 24 hours after the first dose, but requires frequent dosing (three injections a week over six months to a year). Also, it is effective in only about 20 to 30 percent of patients, and carries some serious side effects, including chronic fatigue and depression.
A modified form of interferon named pegylated interferon (after polyethylene glycol, a molecule that is attached to standard interferon) is considered more effective than its predecessor as it has fewer complications with a longer half-life.
It is postulated that one dose of pegylated interferon stays around in the blood and keeps the virus under control the whole week-long and thus is effective in lowering the viral load to a greater extent and for a longer duration.
Thus this newer molecule seems promising in the treatment of chronic hepatitis due to Hepatitis C virus.
Last updated on 13-02-2003
Pediatric Oncall Journal
Syrup formulations of antiretrovirals especially zidovudine and nevirapine are in short supply due to decreased production. How to give prophylaxis to the babies to prevent vertical transmission of HIV_?
Pulverise the adult tablet and give
Do not give prophylaxis to the babies
On humanitarian grounds, the production should be maintained
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