Poisning Center - Pediatric On Call

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katiha...

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POISIONING CENTER

Drug

Treatment Details

Chlorate

Sodium salt {resembles table salt} is more toxic than potassium salt

Route : Ingestion

Fatal dose : 20 to 30gm

Mechanism of action : •It is a powerful osxidising agent and attacks all body cells. It oxidizes hemoglobin to methemoglobin

Clinical picture : •Nausea, vomiting, colicky pain and diarrhea
•Blood, protein and hemoglobin in urine, oliguria, anuria and renal failure
•Hemolysis, jaundice and hepatic failure
•If methhemoglobin levels reach 40 percent or more : agitation, weakness, convulsions and muscular twichings and death due to renal failure

Treatment : •Stomach wash with warm water or sodium bicarbonate
•Methylene blue 25 ml 1 percent solution i.v.and ascorbic acid 1gm
•peritoneal dialysis or hemodialysis
•Symptomatic

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

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