Poisning Center - Pediatric On Call

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katiha...

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POISIONING CENTER

Drug

Treatment Details

Aspirin (acetyl salicylic acid)

It is white crystalline substance with acidic taste. It is commonly used as an antipyretic and analgesic

Route : Ingestion

Fatal dose : 5 to 10 gms

Fatal Period : few minutes to several hours

Clinical picture : Poisoning usually occurs due to idiosyncrasy or consumption of excessive dose
• Irritation of stomach, nausea , vomiting, hematemesis, malena
• Skin rash
• Oedema of face and eyelids
• cyanosis
• giddiness
• pyrexia
• buzzing in ears, vertigo, deafness
• drowsiness
• hypoprothrombinemia
• acidosis, ketosis
• presence of albumin and glucose in urine

Reye’s syndrome: it is sometimes seen in children below 15 years on consumption of aspirin. The main features are acute onset hepatic failure and encephalopathy with residual neurologic manifestations

Treatment : • Emetics
• Gastric lavage with sodium bicarbonate
• Forced alkaline diuresis
• Peritoneal dialysis and hemodialysis
• Vit K to check bleeding
• Symptomatic

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

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