Poisning Center - Pediatric On Call

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katiha...

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POISIONING CENTER

Drug

Treatment Details

Endrin

It is insoluble in water but soluble in alcohol and kerosene oil. it is bitter to taste. it is commonly used as sprays or dusts diluted with inert clays

Route : Ingestion

Fatal dose : 5 to 6gm

Fatal Period : 1 to several hours

Mechanism of action : It interferes with nerve impulse transmission. CNS is first stimulated and then depressed

Clinical picture : • Salivation, nausea , vomiting, abdominal pain
• Hoarseness of voice, coughing, froth at mouth and nose, dyspnoea
• Headache, giddiness, restlessness, hyperirritabilty, dilated pupils, in-cordination, mental confusion, tremors, convulsions
• In non-fatal cases, patient feels well after 24hrs

Treatment : • Clothing should be removed and skin washed with soap and water
• Gastric lavage
• Animal charcoal
• Cholestyramine : increased the fecal excretionof endrin
• Symptomatic

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

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