Poisning Center - Pediatric On Call

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katiha...

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POISIONING CENTER

Drug

Treatment Details

Oleander (Kaner)

They are two varieties:

1}Nerium odorum{white oleander} – having white, pink or red flowers
• Active principle: Nerin and olendrin{glycosides}

2}Cerebra thevetia{ yellow oleander} – having yellow bell shaped flowers, found in temples. All parts of the plant are poisonous

Route : Ingestion

Fatal dose : 15 to 20 gm of root, 5 to 15 leaves

Fatal Period : 24hours

Mechanism of action : •Active principle: erebrin, thevetin, nerifolin, thevetoxin{glycosides}

Clinical picture : •GIT irritation
•Contact dermatitis
•Dilated pupils
•Weak pulse and decreased B.P.
•Twichings, titanic spasm and locked jaw
•Action like strychnine on spinal cord

Treatment : •Stomach wash
•Sodium molar lactate transfusion with glucose and 1atropine, 2mladrenaline nd 2mg noradrenaline is beneficial for cerebra thevetia poisoning
•Anaesthetic agents
•Morphine
•Symptomatic

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

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