Recurrent jaundice with pruritis
Author: Pediatric Oncall
Question.
A 10 months old boy born of third degree consanguineous marriage presented with recurrent jaundice and itching all over the body since 3 months of age. Elder sibling had also died of similar complaints at 8 years of age. On examination, weight was 7.1 kg. Other systems were normal. Investigations showed:
• Bilirubin = 3.6 mg, dl {direct = 2.4 mg, dl}, SGOT = 220 IU, L, SGPT = 240 IU, L, Total proteins = 7.5 gm, dl, albumin = 3.8 gm, dl, GGTP = 150 IU, L, alkaline phosphatase = 3266 IU, L,
• USG Abdomen – Normal
• Liver biopsy – No cholestasis, necrosis or inflammation

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