ESPID 2013
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Diagnostic Dilemma
Diagnostic Dilemma
Diagnostic Dilemma
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FIND DIAGNOSIS
FIND DIAGNOSIS
FIND DIAGNOSIS
Diagnostic Dilemma
Diagnostic Dilemma
Septicemia
Author : Hariom Rawat
Question
A 45 days old child admitted with complain of cough, fever of 8 days. On day of admission baby had temperature of 102-104 f, respiratory rate-60-80 per min, heart rate More than 200 per mint. Total WBC -90,000 per cu mm {n-90 percent}, peripheral blood smear shows toxic granules in 30 percent cells, no malignant cell. X ray chest shows right upper lobe consolidation, bilateral diffuse infiltrate. Blood culture- sterile. Linezolid, meropenem, ofloxacin, amikacin started but 2 days after total WBC was 100000, mm, {n-90 percent}, no radiological improvement, Then chloramphenicol and oral azithromycin were added. Three days after that WBC comes down to 79000, mm. Now after 12days of IV antibiotic, WBC is 51000, mm but fever is still persisting 100-102f, Heart rate-130-160 per min, Resp rate 40-50, min.
Answers of this discussion
Author :- Faizan Bhoira on 03 November 2009.
Answer :- Should also Add Anti malarial and repeat Blood culture and Also 2DE for any e, o SBE and Urine r, m and c, s.

Author :- shilpa on 03 November 2009.
Answer :- This is a case of Septicemia due to Right upper lobe pneumonia. Most probably due to atypical organisms like Chlamydia. Since this child is responding clinically besides fever. Same treatment should be continued in adequate doses and at the same time an effort for definitive etiology by BAL should be done

Author :- Manju Sharma on 03 November 2009.
Answer :- a bone marrow examination for malignancy,along with fungal blood culture and bronchoalveolar lavage for fungal and tuberculosis to be investigated.

Author :- George Paul on 03 November 2009.
Answer :- Klebsiella Pneumonia

Author :- Gaurav Mandhan on 03 November 2009.
Answer :- blood culture sensitivity report is must in view of such high counts and not significant response to all higher antibiotics. What about antenatal history did mother had anything significant predisposing factor like PROM, fever or UTI. Crystalline penicillin can be tried in view of suspected listeria monocytogenes infection which usually presents at extremes of life, can rarely presents like this{ Harrisons}. Other possibility is immunodeficiencies which must be ruled out and if blood culture is not showing any growth then antifungals like amphotericin can be tried and just watch for response.

Author :- Muraliraj N on 04 November 2009.
Answer :- A case of slowly resolving OR resistant pneumonia.. R, O Anatomical anomalies {Obtain HRCT chest} R, O fungal infection and resistant organisms {do bronchoscopy and BAL} Do HIV, also R, O other foci of infection. Also R, O GERD.

Author :- makramgs nagy on 05 November 2009.
Answer :- pertussis

Author :- abdullah bakhsh on 07 November 2009.
Answer :- full septic screen, IV fliuds, empiric antibiotics

Author :- manar aref on 07 November 2009.
Answer :- do bronchoscopy, bronchiolar alv lavage culture to role out TB role out trach eosophageal fistula{H shaped}

Author :- arun kumar on 07 November 2009.
Answer :- do ct chest and blood culture. start antifungal

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
 
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