Introduction:
In spite of many advances in the field of endocrinology, molecular biology and genetics, intersex disorders remain the most challenging clinical situation for the caring physician. It is also very traumatic for the parents and the family of the affected baby. Children with this disorder often present very late particularly in countries like India. Late presentation adds to the complexity of the medical management. Special training of the caring staff and extreme sensitivity of the whole team is necessary for successful outcome.

Definition:
Intersex disorders are suspected when phallus is too small to call it a penis or too large to call a clitoris, or an infant has a short midline cleft separating two folds that could either be two sides of scrotum or unusual looking labia. Such an infant may or may not have palpable gonad(s).

Etiology:
Various disorders at several levels of sexual differentiation from genetic defects to end organ resistance can cause this complex clinical condition. Following conditions are known to cause intersex: