ZInc and ORS - Composition of Reduced Osmolarity ORS

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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ZINC AND ORS

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Introduction

New Reduced Osmolarity ORS

Zinc as Adjuvant in Rehabilitation of Patients with Diarrhea

Recommendations of IAP National Task Force for use of Zinc in Diarrhea

Santosh Singh
Medical Sciences Department, Pediatric Oncall, Mumbai

Address for Correspondence:

Dr Santosh Singh, Medical Sciences Department, Pediatric Oncall, 1/B Saguna, 271/B St. Francis Road, Vile Parle (W), Mumbai 400056.

COMPOSITION OF REDUCED OSMOLARITY ORS

Reduced osmolarity ORS	grams/litre
Sodium chloride	2.6
Glucose, anhydrous	13.5
Potassium chloride	1.5
Trisodium citrate, dihydrate	2.9
Total weight	20.5

Reduced osmolarity ORS	mmol/litre
Sodium	75
Chloride	65
Glucose, anhydrous	75
Potassium	20
Citrate	10
Total osmolarity	245

Recommendations of the IAP National Task Force for use of ORS in diarrhea, August 18-19, 2003 ¹²

All doctors should prescribe ORS for all ages in all types of diarrhea.

The group noted that the new improved universal ORS recommended by the WHO containing sodium 75 mmol/L and glucose 75 mmol/L, osmolarity 245 mOsmol/L is acceptable for all ages and may be made freely available by the Government.

The current formulations ORS A and ORS citrate allowed in the Indian Pharmacopia, 1996 should no longer be used and only the above recommended formulations be in the market.

The powder packet to make 1 liter of solution should be continued. Since mothers tend to use ORS a glass at a time, a measuring device should be included inside to measure the required amount of powder accurately for 200 ml of fluid.

The group was deeply concerned that ORS was not available free of cost at public institutions. It recommended that measures should be taken by the Government to improve its availability and reduce its cost.

The group did not currently recommend marketing of ORS with additives (probiotics,minerals ). They should only be permitted after demonstrating benefit in studies carried out in Indian patients as breastfeeding rates, dietary habits and intestinal flora varies from European and North American children.

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