Investigation of Pyrexia of Unknown Origin/PUO,Treatment of Fever

4th Pediatric Infectious Diseases Conference

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APPROACH TO A CHILD WITH FEVER

Investigations In Pyrexia and Treatment Of Fever

Related topics

Fever and It's Types

Characteristic Features Of Different Types Of Fever

Common Causes Of Fever In Children

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Dr Ira Shah
M.D, DCH(Gold Medalist), FCPS, DNB

Investigations in pyrexia of unknown origin:

Baseline

CBC and peripheral smear examination with ESR

Urine examination

Stool examination

X-Ray chest

Additional tests (as indicated)

Blood culture

Widal test

Liver function tests

Serological tests to antibodies such as for Hepatitis virus, EBV, CMV, Brucellosis, HIV etc.

Paul Bunnel test for infection mononucleosis

Mantoux test

Sputum examination

Auto antibody tests such as RA factor, ANA, ds DNA.

USG Abdomen

Biopsy of affected organ -liver, lymph nodes, bone marrow.

Total body CT or MRI scanning.

Treatment of fever:
For fever less than 100 degree F, tepid sponging to bring down the fever is recommended. Antipyretics are recommended for fever >100 degree F or for fevers not coming to normal.

Acetaminophen (10mg/kg/dose PO/PR/IV every 6-8 hourly)

Nimesulide (5mg/kg/day PO every 8-12 hourly)

Non-steroidal anti-inflammatory agents such as Ibuprofen (5-10mg/kg/
dose PO every 6-8 hourly) are useful.

Last created on 23-02-2001
Last updated on 28-04-2007

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