Ocular Morbidity in Premature Children:Retinopathy of Prematurity,ROP

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OCULAR MORBIDITY IN PREMATURE CHILDREN

Related topics

Introduction

Pathophysiology

Classification of ROP

Role of Pediatricians in ROP

Other Vision Threatening Ocular Morbidity

Mihir Kothari*, V. Narendran**, Parag K. Shah***
*MS, DNB, FPOS, Diploma in Pediatric Ophthalmology and Strabismus ( USA ),
Director, Jyotirmay Eye Clinic and Pediatric Low Vision Center,
205 Ganatra Industrial Estate,
Pokhran Road No1,
Thane (W) 400 601,
Maharashtra, India

** DNB, Chief Medical Officer and Head of the Vitreo-retinal Services,
Aravind Eye Hospital and Post Graduate Institute of Ophthalmology,
Avinashi Road, Coimbatore 641 014,
Tamilnadu, India.

*** DNB, Consultant, Vitreo-retinal Services,
Aravind Eye Hospital and Post Graduate Institute of Ophthalmology,
Avinashi Road , Coimbatore 641 014,
Tamilnadu , India .

Corresponding author:
Mihir Kothari : drmihirkothari@yahoo.com

Retinopathy of Prematurity :

The most common eye disease of prematurity is retinopathy of prematurity (ROP). 2 The frequency and severity of this disorder is inversely related to the gestational age and birth weight (Table 2 and 3).

Table 2: Incidence of ROP in the babies born at different Gestational Age

Gestational Age	Incidence of ROP
> 32 weeks	< 6%
< 31 weeks	30%
< 28 weeks	83%

Table 3: Incidence of ROP in the babies of different Birth Weights

Weight	Any ROP	Prethreshold	Threshold
< 750gm	90%	39%	15%
750-999	78%	21%	7%
1000-1250	46%	7.30%	2%

Damage in ROP ranges from minor to catastrophic . Many risk factors other than gestational age and the birth weight are also associated with higher incidence of ROP. They are listed in table 4.

Table 4: Risk factors for ROP 3-15

Established Risk Factors 3-5	Potential Risk Factors 6-13	Confirmed as not Risk Factors 14,15
Prematurity	In-vitro fertilization (IVFET) and Multiparity 6-8	High light levels 14
Birth weight	Intraventricular hemorrhage, Neonatal Seizures and Cerebral Palsy 9	Hyperbilirubinemia 15
Oxygen	therapy Anemia 10,11
	Blood transfusion 10-12
	Sepsis 13
	Bronchopulmonary dysplasia 10
	Vitamin E deficiency

Next : Pathophysiology

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