Greater than 10 degrees of difference in the talar tilt when compared to the nonaffected side is suggestive of an injury to the CFL.Proximal to the lateral and medial ankle ligaments, the distal tibia and distal fibula are connected to each other by a series of tough fibrous structures collectively referred to as the tibiofibular syndesmosis. The three individual components which make-up this syndesmosis include: a) anterior tibiofibular ligament, b) posterior tibiofibular ligament, and c) intraosseous membrane.

Note that on this diagram, the PTFL stands for the posterior talofibular ligament (not the posterior tibiofibular ligament). The posterior tibiofibular ligament is NOT drawn on this diagrammatic view. Clinically one can check for injuries of the tibiofibular syndesmosis by the squeeze test. To perform this test, the examiner firmly grasps the patient's lower leg (around the lower aspect of the calf), and gently squeezes the tibia and fibula together.