NEPHROTIC SYNDROME
Last Updated : 1/6/2011
Kumud P Mehta
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Nephrotic syndrome

is characterized by generalized edema as a result of

hypoproteinemia

due to excessive protein loss in the urine. Hypercholesterolemia is commonly associated with MCNS. The causes of increased permeability of glomeruli to proteins is not known in 90% of children with nephrotic syndrome hence it is called as idiopathic or primary nephrotic syndrome. Majority i.e. 80 - 85% of NS respond to

steroid therapy

and if biopsied will show minimal change.



Contributor Information and Disclosures

Kumud P Mehta
Consultant Pediatrician & Pediatric Nephrologist, Jaslok Hospital & Research Centre, Bai Jerbai Wadia Hospital for children, Mumbai, India


First Created : 1/3/2001

References

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