Malabsorption Syndromes,Maldigestion,Absorption,Digestion Types

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MALABSORPTION SYNDROMES

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Causes of Malabsorption in children

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Malabsorption Syndrome Faq's

Dr. Saumil K. Shah
MD, DNB, DM, DNB
GASTROENTEROLOGIST, HEPATOLOGIST, ENDOSCOPIST

Honorary Consultant: Lilavati Hospital And Research Centre

Q. What is digestion and what is absorption?
A. Digestion means hydrolysis of nutrients. Absorption means uptake of nutrients from the gastrointestinal tract to the systemic circulation.

Q. What is maldigestion and what is malabsorption?
A. Maldigestion denotes impaired nutrient hydrolysis. Malabsorption refers to defective mucosal absorption of nutrients. However, the two entities are so closely linked that in clinical practice malabsorption serves as a global term for all aspects of their impairment. Malabsorption may occur for many nutrients or for specific carbohydrates, fats, or micronutrients.

Q. What steps are involved in digestion and absorption?
A. Three phases are involved:

Luminal phase - Dietary fats, proteins and carbohydrates are hydrolyzed and solubilized, largely by pancreatic and biliary secretions.

Mucosal phase - Terminal hydrolysis of carbohydrate and peptides occurs and fats are processed and ;then packaged for cellular export.

Removal phase - Absorbed nutrients enter the vascular or lymphatic circulation.

Thus defect in any of these phases leads to malabsorption.

Next : Causes of Malabsorption

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