Age Group Affected,Burden,Disease Spectrum of Hib Infection

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

Immunization and Vaccination

Hib Vaccine

Immunization and Vaccination

BCG Vaccine

Chickenpox or Varicella Vaccine

DPT Vaccine

Frequently asked questions on immunization

Hepatitis A Vaccine

Hepatitis B Vaccine

Hib Vaccine

Human Papillomavirus vaccine

Immunization Schedule

Influenza vaccine

Measles Vaccine

Meningococcal vaccine

Polio Vaccine

VACCINE REMINDER

Get the Vaccine Schedule for your child."

Today's Poll

Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

Vote

Results

HIB VACCINE - LATEST UPDATES

Related topics

Hib Vaccine Overview

Severity and Incidence of Hib Infection

Generations of Hib Vaccines

Hib Vaccines Frequently Asked Questions

Dr Nitin Shah
Hon. Pediatrician, UHC, LTMG Hospital, Mumbai.
Treasurer, Indian Academy of Pediatrics, 1998-2001

Q. What is the disease spectrum of Hib infection?
A. Hib infection usually leads to invasive disease like meningitis, epiglottitis, pneumonitis, cellulitis, arthritis, septicemia etc. Of the invasive H. influenzae infections in children, 99% are due to type b and rarely due to type a or other non- typeable H. influenzae organisms.

Various studies show that 15- 20% of cases of ALRI and 30- 40 % cases of pyogenic meningitis are due to Hib infection

Q. What is the spectrum of non-type b H. influenzae infection?
A. Non-type b & non - capsulated H. influenza infection commonly lead to upper respiratory tract infections, otitis media, sinusitis, chronic respiratory tract infection and other non- invasive infections especially in children> 7 years of age.

Q. Which age group is affected by Hib infections?
A. Hib infection is most commonly seen in children < 5 years of age. The mean age of onset is 6-24 months after which it declines gradually till 5 years. 95% of Hib infections occur before 5 years of age.

Higher the incidence of Hib in community, earlier is the age of onset, more is the chance of meningitis and less is the chance of epiglottitis. In developed countries 10% of Hib disease occurs before 6 months of age, 40% by 1 year and 75% by 2 years. In developing countries 45% of total Hib infections occur by 6 months of age and 65 - 75 % by 1 year. This has a bearing on the immunization strategy, as earlier the age of onset (like in India), earlier should be the completion of 3 primary doses of Hib vaccine.

Q. What is the burden of H. influenza b infections?
A. Annual incidence of Hib meningitis varies from country to country. It varies from 35 - 300 cases / 1,00,000 children <5 years of age. In developed countries it is low, like in USA before universal Hib immunization, it was 60 - 70/1,00,000 children <5 years of age and in Europe 35/100,000 children <5 years of age. In developing countries, it is higher e. g. in Alaska it is 300/100,000 children <5 years of age.

In the west, of the total cases of invasive Hib disease, 40-75% present with meningitis, 25 % with epiglottitis and 25% with rest of the illnesses. Higher the incidence, higher is the rate of meningitis and lower is epiglottitis. In India, IDIS study has shown that of the total cases of Hib diseases, 66% present as meningitis, 7% as pneumonitis, 7% as skin and soft tissue infections, 7% as sepsis and rest as other manifestations.

Next : Severity and Incidence of Hib Vaccine

<< Hepatitis B Vaccine

>> Human Papillomavirus Vaccine

Mail To Your Friend

Print This Article

TOP SEARCH TERMS

Human Papillomavirus vaccine

Immunization and Vaccination Schedule

Influenza Vaccine

Measles Vaccine

Meningococcal Vaccines

MMR Vaccine

Conjugate Pneumococcal Vaccine

Diseases & Conditions

Pediatric Oncall Journal

Pediatric Conferences

Ped Tools

Adverse Drug Reactions

Pediatric oncall book store

Partner Sites

Infection in Children

Pedcall

Medical ADRIS

Vaccine Reminder

Pediatric Oncall Journal

Educational Section

Disclaimer:

The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.

Sitemap For Doctor

Sitemap For Parent

Sitemap For Kids