4th Pediatric Infectious Diseases Conference
 
 
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Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Polio Vaccine
Polio Vaccine

Polio (poliomyelitis) mainly affects children under five years of age. Polio virus invades the nervous system and can cause total paralysis in a matter of hours. Polio is mainly passed through person-to-person (i.e., fecal-oral) contact, and infects persons who do not have immunity against the disease.

Polio Eradication Campaign :
In 1988, the forty-first World Health Assembly, consisting then of delegates from 166 Member States, adopted a resolution for the worldwide eradication of polio. It marked the launch of the Global Polio Eradication Initiative, spearheaded by the World Health Organization (WHO), Rotary International, the US Centers for Disease Control and Prevention (CDC) and UNICEF. The primary strategies for achieving this goal are:

  • high infant immunization coverage with four doses of oral poliovirus vaccine (OPV) in the first year of life;

  • supplementary doses of OPV to all children under five years of age during national immunization days (NIDs)

  • surveillance for wild poliovirus through reporting and laboratory testing of all acute flaccid paralysis (AFP) cases among children under fifteen years of age;

  • targeted "mop-up" campaigns once wild poliovirus transmission is limited to a specific focal area.

Polio cases have decreased by over 99% since 1988, from an estimated 350,000 cases then, to 1604 reported cases in 2009. However, polio eradication campaign is way behind where its planners hoped it would be at this stage. There are still four countries (Nigeria, India, Pakistan and Afghanistan) in which transmission has never been interrupted. Furthermore, 14 countries in which poliomyelitis had been eradicated have reported re-introduction, admittedly small numbers of cases, but showing that the threat is still quite real. Persistent pockets of polio transmission in northern India, northern Nigeria and the border between Afghanistan and Pakistan are the current focus of the polio eradication initiative.

National immunization Days/ Pulse polio immunization
Pulse Polio Immunization (PPI) involves providing additional OPV doses to every child aged <5 years at intervals of 4-6 weeks. The aim of PPI is to "flood" the community with OPV within a very short period of time, thereby interrupting transmission of virus throughout the community. In 2005, new monovalent polio vaccines (mOPV type 1 and type 3) were licensed and used to enhance the impact of supplementary immunization activities (SIAs) in the key remaining reservoirs of wild polio. Despite the use of mOPVs and the intensification of the global eradication efforts in 2007, indigenous wild poliovirus type 1 (WPV1) and 3 (WPV3) transmission has continued.


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