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Question Category:Genetic disorders

Dear sir 1. 1y old infant with O.I,family history is +ve for another male how can you help him...?     Check out the answer

Question Category:Genetic disorders

I was managing a child with IEM in peads ICU.he was having persistent metabolic acidosis and i had to start him on NaHCO3 infusion 4.2%.then slowlyincreased the infusion form 1cc/hr to 3 cc/hr.but the problem started when the NA serum level increased to 180mEqq/l.so i had no choice to reduce the infusion .but the met acidosis rebound adn the bp crashed.so i started back the met bicarb and di dnot bother about the high sodium.whatr else could have been done.can i start frusemide infusion for this patient to reduce sodium     Check out the answer

Question Category:Genetic disorders

I was wondering, if a condition is found in a child and it turns out to be genetic are both parents tested to see who it comes from?. From genetic testing can you find out if the father is the true biological father if the condition can only be passed on by one of the parents and neither parent carries that particular gene? If from genetic testing you find out that the father is not the true biological father does the doctor/health team have a legal obligation to inform the father in question? I would be happy if you could answer these quetions as i'm unsure as to how genetic testing works and to how much information you can find out from undertaking a genetic test.     Check out the answer

Question Category:Genetic disorders

Any effective therapy for leukodystrophy? except for Lorenzo's oil (in select cases). How to control seizures in them? Most importantly how to apprach to manage and prognosticate such kids? This site does not have single search result on it?     Check out the answer

Question Category:Genetic disorders

3 ytears female child born by section at term,because of non proress due to feto-pelvic disproportion.She had an apgar score of 8-9. She was kept in incubator for three ds because of LBW 1900 gms. Dicharged in good gen condition on breast milk, the baby shoud moderate floppiness.. and delay of developmental psychomotor milestones. thourough investigations including kary typing, aminoacid screaning,metabolic diseases did not show any abnormality, CBC,, WBCs,BS,liver and kidnye teast were all within normal values. I saw the child for the first time last week clinical examination ..10.5 kgs girl,with poor slugish spontaneus movement,, needs help to initiate standing and wlking,, proceedics wit assistance blood presure 100/65 mmHg ,Ht 93 cm and HC 48 cm her attitude seemed to be like autism children with poor interest with surroundin heart and lungs were within normal,abdomen soft non tender , no organomegaly the only abnormal finding was the shape of both wrists they looked like hsving lower radis fracture and a very small extra phalanx with with clear articular movement at that level to recieve a dignotic hint or suggetion I `be very thankfull and apreciate     Check out the answer

Question Category:Genetic disorders

Medical line of management in treatment of osteogenesis imperfecta?? role of biphosphonates??     Check out the answer

Question Category:Genetic disorders

I have a child 5 yr with progressive muscle weakness begining with frequent falls initially and now not able to walk. this hAS happenned over 2-3 years. no history of convulsions. mentally normal. non consanguinous marriage. fits in sma but the genetic study i.e SMN gene and the NAIP gene are normal. can we have sma with these genes normal. sachin d
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