Neonatal Seizures FAQs - Pediatric Oncall

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katihar...

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Question Category : Neonatal Seizures
A 6 month old male presented with 2 months history of seizures. He was thoroughly investigated with neuroimaging (MRI) which was normal. Biochemical parameters (RBS, CALCIUM, MAGNESIUM,POTASSIUM,CHLORIDES) were repeatedly normal, EEG was normal and done twice during inter ictal period. The boy was born of a cesarean section with normal APGAR. Had one episode of seizure on 4th day of life which was due to hypoglycemia since the mother was known to be diabetic and was on insulin since the second trimester. The boy had an uneventful recovery following treatment with glucose at that time and was apparently normal for 4 months with normal growth and milestones. phenytoin was started at 7mg/kg dose and was increased to 10mg/kg/day because of recurrent episodes of seizures. Has seizures every 10-15 days which are serial seizures and is being admitted into NICU for phenytoin loading dose which he received thrice till now in the span of 2 months. Then phenobarbitone at 5mg/kg has been started after the recent serial seizures which occurred on phenytoin 10mg/kg. Seizures are generalized with loss of consciousness. Never had a status epilepticus. Occurs even during sleep and also during activity. General examination is unremarkable. All systems are normal. Check Out the Answer
Question Category : Neonatal Seizures
I would like information on benign neonatal myclonus of sleep. Please include the prognosis of this condition. Thanks. Check Out the Answer
Question Category : Neonatal Seizures
Can neonatal septicaemia without a meningitis component and without hypoglyceamia nor hypocalcaemia cause convulsion? Check Out the Answer
Question Category : Neonatal Seizures
If you are given a choice between exchange transfusion and immunoglobulins as therapeutic option in a neonatal case of severe septicemia- 1.which one you will opt for? 2.what is the frequency/or duration/dosage that you will give for. 3.what is your clinical experience regarding this? Check Out the Answer
Question Category : Neonatal Seizures
Can anybody give me the reference of "Use of Quinolones in neonatal sepsis"? Check Out the Answer
Question Category : Neonatal Seizures
In neonatal seizures we discharge the baby on phenobarbitone. But this drug is known to have adverse effect on the neuromotor outcome if used for a long time. Is there any alternative to this? Does anybody use /recommend any other drug? Check Out the Answer
Question Category : Neonatal Seizures
Hello - Our son was born on 11/19/2004. At birth, he had swallowed amino fluid and during the first 3 days - he had to be extensively cleaned for the fluid. While doing this, he had developed respiratory stress and he had a swollen track. On the day 4 we found that he had developed seizures and there were extensive tests that were conducted. The only deficiency was the calcium levels which read around 6 mg/dl. He was treated for seizures and he was treated with a calcium supplement of 1.6 cc of Calcium gluconate - 4 times a day initially. He is now in his 5th week with a calcium suppliment of .8 cc oral suppliment and we have also discovered that his Vitamin - D level is slightly below normal - with a reading of 12 (where the normal reading should be 20 - 100). We are worried that he will develop some other complications. Kindly advice on this and as much information will be appreciated on this. Anxious parents - Kaveri and Madhu. Check Out the Answer

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

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