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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katihar...

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Question Category : Puberty
A 10 years old female with complains of---- 1} virilization ---- deep voice , excess facial hairs , clitoris enlarged 2} headache in the occipital region 3} generalized weakness [ virilizing changes noticed around 5-6 yrs of age] PAST HISTORY--- fever with convulsion at 2 yr of age, hospitalized for 5 days ON EXAMINATION --- wt & ht normal p -- 102/min menarche not attained r/r -- 24/min generalized skin hyperpigmentstion (+) bp -- 100/70 mmhg breast- prepubertal RS/CVS/CNS-- NORMAL EXTERNAL GENITALS-- dense pubic hairs with significant clitoris enlargement. few I/G done 3-4 yrs back--- 1] mri brain-- microadenoma in anterior pitutary 2] serum estrogen & progestrone -- normal 3] usg abdo-- uterus/ovary normal Q1-how to corelate pitutary adenoma with virilization? Q2-how to further investigate this pt? Q3- what should be the plan of management? Please help me sir to understand this case. Thank you sir. Check Out the Answer
Question Category : Puberty
A 14 year child boncm presented with delayed puberty and short stature. Her examination showed infantile genitalia with tanner stage 1.no other finding such as features of turner syndrome. Her USG abdomen shown agenesis of uterus normal kidney and no other anomalies. What should be further investigations? What are the differential diagnosis? Check Out the Answer
Question Category : Puberty
Hello Dr. Meena, My daughter is 71/2 years old.. She is developing pubic hair and there is a slight hair growth in her under arm region. In fact I spotted her first pubic hair when she turned 5. There is absolutely no development of breasts. She weighs 26 kgs and is of normal height. She's a very bright girl and outwardly there is no sign of any physical abnormality. Is this a case of precocious puberty? What kind of tests should I go in for and treatments? Kindly advice. Check Out the Answer

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

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