4th Pediatric Infectious Diseases Conference
 
 
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Autoimmune Disorder
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Specialist Answers
Question
Dear sir a 16 year old female present with painful petechial eythematous lesion in both lower legs seen by dermatologist, diagnosed as vasculitis. The patient gave history of GN 6 years ago. Now she is on captopril+propranol+prednisolone for the last 3 years. Prior to that she was given cyclophosphamide for 4months. On exam. Obese healthy, vital sign are normal, GUE is normal apart from trace albumine, renal function are normal. My questions are; 1.Any relation between vasculitis and activity of the disease . 2.Can we taper the treatment or does she need treatment now. . 3.Is renal biopsy indicated. I am waiting reply thanks.
Answer
What is the reason for captopril, propranolol and steroids for so long? Since she had glomerlonephritis and now vasculitis, one should rule out Hencoch Schnolein purpura and also SLE. A kidney biopsy would be required if not done before and immunofloresense would be essential.
 
 
 
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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
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