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Question

I have a female pt aged 2 yrs weighing 10kg.She is born to nonconsanguinous parents.She is suffering from malar rash since infancy.Her investigations report are as follows: ANA - +ve dsDNA -ve anticardiolipin ab +ve RAsso +ve RAllb -ve C3 &C4 normal Basing on the clinical and lab findings I have diagnosed her to have SLE.Further investigation do not reveal any other organ except skin involved at present. WHAT IS THE LINE OF MANAGEMENT ? What medicines to be used? What are the doses? How long to use? Chloroquin or steroid or both? Doses and duration? Any newer developed medicines? Kindly give reply in detail.

Answer

It is quite unusual to have a patient with active SLE with positive ANA and normal C3. Also 2 years of age is young age of onset. You need to reverify your diagnosis of SLE before you decide to treat her. Take a skin opinion and rheumatolog opinion.
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