4th Pediatric Infectious Diseases Conference
 
 
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Specialist Answers
Question
Is there a relationship between zinc level and childhood leukemia (ALL)? Is it higher or lower in leukemic children & does treatment affect the level of serum zinc?
Answer
It has been noted that leukemic cells contain much less zinc than normal lymphocytes which may be very important, since zinc is vital for proper genetic and cellular function. Zinc metabolism deviations have been recognized in leukemia since 1949, but are not well understood, although zinc was used in the early 1950s as a therapeutic drug in the treatment of leukemia. Zinc may function therapeutically in leukemia by augmenting L-asparaginase in killing leukemic cells (since a zinc deficiency may induce free asparagine), and by stimulating cell mediated immunity.


Ref:Medical Hypotheses. 2005;64:1124-1126
 
 
 
Pedi Poll
Today's Poll
Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?
No, it should be used only after drug sensitivity report
Yes, under guidance of an infectious disease expert
Educational Section
 
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