8 years old boy for non consanguineous parent complain one and half years ago of generalized muscle ache and recurrent falling and numbness especially at finger tips plus burning sensation there and some times arthralgia in elbow and knee joints parents observed laxity of his joints especially at elbow joint and wrist joint with moderate ability of acrobatic movement at these mentioned joints 1 year ago they seek for medical advice after observing the progressive course of this manifestation and many investigations were done which all show normal values examination show normal looking child with mild obesity no special facieses observed with normal mental status. abdomn examination - lax mobile with no rigidity or tenderness or organomegaly chest examination normal heart examination shows mild prolepses at mitral valve which was confirmed by echo on heart head neck examination normal no lymphadenpathy nor organo megaly neurological examination show mild reduction in muscular motor power with with intact sensation motor reflexes normal away from laxity of joints especially at elbow and wrist joint with some acrobatic movements observed and mild hypertrophy of muscle of calf and deltoid no other abnormalities in muscular system investigations were as follow/ s.urea and s.creatinin = normal s. calciium total =10.3 serum phosphorus =6.7 normatl (3-6) ck -total =122 repeated one month later and found to be 70 normal up to 195 esr 1st hour 12 and 2nd 25 na=145 s.potassum 4.5 s.magnessuim =201 n(1.2-2.1) antids-dna negative rf and crp negative asot=200 tu cbc away from mild thrombocytosis 415000 no abnormality in blood picture was observed with norma defferential count emg conclusion (slight reduction in the inter ference pattern and normal sensorimotror conduction can any one have suggestions? or help? thanks doctor Reda Fadle … egypt email- dr_reda63@hotmail.com cell number 0020106576936