User Name Password Remember Me  
New User Register Forgot Password ? Change Password
 
 
Get Diagnosis
Difficult Cases
Grand Rounds
Spot Diagnosis
Discussion Forum
Blog
Poll
Online MCQ's
 
New Sections
  
Video Podcast
Audio Cast
Mobile(WAP)
  Pedi Poll  
Should Phase 1 Clinical Trials be allowed in India?
Yes
No
  Translate This Page  
 
SPECIALIST ANSWERS

Question
3.5 yrs girl,II degree consaguinity product,2 normal older sibs,mother had jaundice in 1st TM of pregnancy,mild dev.delay. Had grade I hepatic encephalopathy with HAV 6mths back. 3 episodes of para/quadriparesis of mod-severe degree & loss/grossly altered speech lasting for 5-10days over last 15 mths.fever ppt.once,focal seizures once. Workup(KEM-PUNE)-gen.Spikes & wave on EEG,CT(old)-WNL,MRI-enhancement-rt.temporal/parietal lobes & choroid plexus,normal myelination.blood & csf lactates raised. LFT-WNL. ?MELAS/Leighs suggest diagnosis & further workup...

Answer
Since CSF lactate is raised and there have been 3 episodes of encephalopahty, one must work up for inborn error. A urine organic acids and urine for dicarboxylic acid should be done. Do a serum ammonia. Also and EMG to look for myopathy. A muscle biopsy may be indicated if strongly suspecting MERRF or MELAS. Specific enzyme analysis will depend on the further workup .
  Grants  
 » Apply For Research Grant
  Search  
Hospitals
Pediatrician
Special Schools
Medical Colleges
Pediatric Residency
Pediatric Conferences
Jobs & Vacancies
Journals
NGO's
  Ped Tools  
Pediatric Calculator
Drug Index
Medical Equipment
Vaccine Reminder
Adverse Drug Reactions
Biochemical Profile
Online MCQ's
  Calculators  
+ Growth
+ Conversion
+ Renal
+ Pregnancy
+ Blood Pressure
+ Blood Group
+ Critical Care
+ Drug Dose
+ Diarrhea Solution
+ Reference Values
+ Antibody Test
+ Drug Interaction
 
 
Parent Corner l Kids Corner l Terms & Condition | Privacy Statement l Advertising l Feedback l Awards
About Us l Link to Us l Site Map l Shopping Mall  
Partner Sites
 HIV in Children  Infection in Children  Pedcall  Medical ADRIS  Vaccine Reminder  Pediatric Oncall Journal

Copyright© 2000-2008 All rights reserved with Pediatric Oncall

Disclaimer:The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitue an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.

 
Sitemap For Doctor | Sitemap For Parent | Sitemap For Kids Site designed and maintained by Levioza